Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLD1 All Species: 30.91
Human Site: Y484 Identified Species: 45.33
UniProt: Q13393 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13393 NP_001123553.1 1074 124184 Y484 V G G I D L A Y G R W D D N E
Chimpanzee Pan troglodytes XP_526380 1125 128795 V547 P D H V S S T V Y L W A H H E
Rhesus Macaque Macaca mulatta XP_001085464 1074 124020 Y484 V G G I D L A Y G R W D D N E
Dog Lupus familis XP_545291 1075 123911 Y484 V G G I D L A Y G R W D D N E
Cat Felis silvestris
Mouse Mus musculus Q9Z280 1074 123950 Y484 V G G I D L A Y G R W D D N E
Rat Rattus norvegicus P70496 1074 123795 Y484 V G G I D L A Y G R W D D N E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513744 295 33781
Chicken Gallus gallus XP_422793 1072 123414 Y482 V G G I D L A Y G R W D D D E
Frog Xenopus laevis NP_001129642 1039 119219 W462 M S S S V Y L W A H H E K I V
Zebra Danio Brachydanio rerio NP_001153567 1022 117847 R444 H P N I K V M R H P D H V S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001137610 1364 155352 Y721 M G G I D L C Y G R W D D H H
Honey Bee Apis mellifera XP_001121004 1135 129725 Y513 L G G I D L C Y G R W D N N E
Nematode Worm Caenorhab. elegans NP_494939 1427 163517 F661 V G G V D L C F G R W D D H R
Sea Urchin Strong. purpuratus XP_784455 790 90080 H277 G V M L W A H H E K G V I I D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M9W8 1046 118792 I454 S K K R L Q N I H K N V K V L
Baker's Yeast Sacchar. cerevisiae P36126 1683 195185 P669 T S T P W S K P N R F G S F A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.7 97.8 91 N.A. 91 90.6 N.A. 22 79.4 75.6 66.6 N.A. 34.8 40.3 35.9 35.1
Protein Similarity: 100 92 99 95.1 N.A. 95.6 95.6 N.A. 24.8 88.8 86.3 78.3 N.A. 50.9 57.7 51 49.5
P-Site Identity: 100 13.3 100 100 N.A. 100 100 N.A. 0 93.3 0 6.6 N.A. 73.3 80 66.6 0
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. 0 100 20 20 N.A. 86.6 93.3 86.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. 30.6 21 N.A.
Protein Similarity: N.A. N.A. N.A. 50.6 35.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 7 38 0 7 0 0 7 0 0 7 % A
% Cys: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 57 0 0 0 0 0 7 57 50 7 7 % D
% Glu: 0 0 0 0 0 0 0 0 7 0 0 7 0 0 50 % E
% Phe: 0 0 0 0 0 0 0 7 0 0 7 0 0 7 0 % F
% Gly: 7 57 57 0 0 0 0 0 57 0 7 7 0 0 0 % G
% His: 7 0 7 0 0 0 7 7 13 7 7 7 7 19 7 % H
% Ile: 0 0 0 57 0 0 0 7 0 0 0 0 7 13 0 % I
% Lys: 0 7 7 0 7 0 7 0 0 13 0 0 13 0 0 % K
% Leu: 7 0 0 7 7 57 7 0 0 7 0 0 0 0 7 % L
% Met: 13 0 7 0 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 7 0 0 0 7 0 7 0 7 0 7 38 0 % N
% Pro: 7 7 0 7 0 0 0 7 0 7 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 7 0 0 0 7 0 63 0 0 0 0 7 % R
% Ser: 7 13 7 7 7 13 0 0 0 0 0 0 7 7 7 % S
% Thr: 7 0 7 0 0 0 7 0 0 0 0 0 0 0 0 % T
% Val: 44 7 0 13 7 7 0 7 0 0 0 13 7 7 7 % V
% Trp: 0 0 0 0 13 0 0 7 0 0 63 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 0 50 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _